• Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe
  • Sweet Melissa’s Cafe

Sweet Melissa’s Cafe

1625 Periwinkle Way, Sanibel, FL 33957


> Takeout Available> Delivery Available> Reserve a Table

icon-ratings-reviewsRatings & Reviews


94% Positive Reviews

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Experience the award-winning Sweet Melissa’s Cafe, Sanibel Island. Serving lunch and dinner, this is a culinary journey of epic proportions! Executive Chef Melissa Talmage challenges your taste buds to explore a creative menu with a wide array of different tastes, textures and eclectic ingredients. Named “Best Dining in Lee County” by Gulf Shore Life and placed on USA TODAY’S “10 Best Restaurants in South Florida,” Sweet Melissa’s Cafe exudes warmth and impeccable service. Fine linens and a cozy bar add to the experience, while soothing live acoustic jazz sets the mood on select evenings. Guests who prefer to dine al fresco will find the screen-in patio a delightful option.


1625 Periwinkle Way, Sanibel, FL 33957

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icon-dining-amenitiesDining Amenitiesicon-chevron-down

icon-cuisine-typeCuisine Type
Contemporary American
icon-meals-servedMeals Served
Tuesday - Friday
12:00 pm - 8:00 pm
5:00 pm - 8:00 pm
Closed Sunday
icon-valetParking Details
icon-dining-informationDining Information
Full Bar
Outdoor Dining
Wine List
icon-musicLive Music
Friday & Saturday Evenings
icon-additional-servicesAdditional Services
Private Dining
icon-payment-detailsPayment Details
American Express

icon-chef-infoChef Info

Executive Chef Melissa Donahue

Executive Chef Melissa Donahue’s resume is impressive, with training at Manhattan’s French Culinary Institute followed by the kitchens of some of the most respected restaurants in the United States including Union Cafe in New York City, Commander’s Palace in New Orleans and John Besh’s August, also in New Orleans.

Originally planning to pursue a law degree, Donahue – Talmage changed career paths after her first child was born and she realized she would rather spend her time in the kitchen instead of a courtroom. Hurricane Katrina blew Chef Melissa out of New Orleans, landing her on Sanibel Island and correlating nicely with a job offer from the former Redfish Blufish restaurant. In 2009 the restaurant was renamed and opened as Sweet Melissa’s Cafe.

With her culinary and management talents consistently praised, Chef Donahue – Talmage has received high praises from every major publication in Southwest Florida, with recipes featured in multiple local travel and restaurant guides. At the 2010 Sanibel Island Taste of the Island, she was awarded first place for Best Appetizer. 2011 saw her selected as the “Best Chef for a Chef” Vintner Dinner in the Southwest Florida Wine & Food Fest. The popular on-line dining reservation website, Open Table, recognizes the restaurant with Diners’ Choice Awards, including Best Food, Best Overall and Best Service. In 2017 Sweet Melissa’s Café was recognized by USA Today as a top 10 restaurant in South Florida. With a menu and true talent that keeps diners begging for more, Sweet Melissa’s Cafe and Chef Melissa Donahue – Talmage are “Creatively Out Of The Ordinary”.


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